How phenol is used in the manufacture of drugs like aspirin?
Asked by Topperlearning User | 27th Mar, 2014, 03:43: PM
Expert Answer:
- Phenol first needs to be treated with NaOH that will give sodium phenoxide.
- Sodium phenoxide when treated with CO2 at 400K under 4-7 atm pressure followed by acidification gives 2-hydroxy benzoic acid (salicylic acid as the main product).
- Salicyclic acid is the starting material for the manufacture of 2-Acetoxybenzoic acid(aspirin) which is used for relieving pain and to bring down the body temperature.
Answered by | 27th Mar, 2014, 05:43: PM
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