clotting of blood

Asked by sahil.95rana | 7th Jul, 2010, 06:56: AM

Expert Answer:

Hi Sahil,
Three major steps of blood clotting are-
1. Blood platelets disintegrate and release platelet factor- 3 and thromboplastin. These two factors combine with calcium ions to form prothrombinase.
2. The prothrombinase inactivates heparin (anti-coagulant), and helps prothrombin to break down into thrombin and small peptide fragments.
3. Thrombin depolymerizes fibrinogen and forms fibrin. This fibrin forms a dense network with blood cells and platelets and a clot is produced.

Answered by  | 15th Jul, 2010, 06:13: PM

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