how can cistiene crosslink?

Asked by alice | 15th Aug, 2015, 11:38: AM

Expert Answer:

Cysteine contains a highly reactive thiol group and therefore under oxidizing conditions a disulpide bond is formed between a pair of cysteines. In other words, the two substituted cysteines are cross-linked via formation of a disulfide bond. 
Cysteine play a valuable role by crosslinking proteins, which increases the rigidity of proteins and functions to increase proteolytic resistance. Inside the cell, disulfide bridges between cysteine residues within a polypeptide, maintains the protein's tertiary structure. Insulin is an example of a protein with cystine crosslinking

Answered by Hanisha Vyas | 16th Aug, 2015, 11:04: AM