HOW RECEPTORS ACT AS DRUG TARGET ?

Asked by RAHUL | 13th Apr, 2013, 09:35: PM

Expert Answer:

To describe a native protein in the body whose activity is modified by a drug resulting in a desirable therapeutic effect. In this context, a biological target is often referred to as a drug target.
Receptors are proteins that are crucial to body’s communication process. Majority of these are embedded in cell membranes. Receptor proteins are embedded in the cell membrane in such a way that their small part possessing active site projects out of the surface of the membrane and opens on the outside region of the cell membrane. In the body, message between two neurons and that between neurons to muscles is communicated through certain chemicals. These chemicals, known as chemical messengers are received at the binding sites of receptor proteins. To accommodate a messenger, shape of the receptor site changes. This brings about the transfer of message into the cell. Thus, chemical messenger gives message to the cell without entering the cell.

Answered by  | 15th Apr, 2013, 12:41: PM

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