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CBSE Class 12-science Answered

describe transforming principle given in Griffiths experiments
Asked by lalit786803 | 16 Jun, 2020, 09:51: PM
Expert Answer
S. F. Griffith in 1928 studied pathogenicity of different strains of bacterium Streptococcus pneumoniae in mice.
He worked with two strains of Pneumococcus bacteria—type III-S and type II-R.
The major difference between these two types of strains is that the type III-S strain has a smooth polysaccharide coat which makes it resistant to the immune system of mice, whereas the type II-R strain lacks this coat and thus will be destroyed by the immune system of the host.
The experiment performed by Griffith is summarised below:

The occurrence of the living S-type virulent bacteria is possible only by their formation from the R-type non-virulent bacteria which pick up the trait of virulence from dead bacteria. This phenomenon is called Griffith’s effect or transformation.
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