During the Rh pregnancy factor if the mother has negative blood group and the foetus has positive blood group. Then the stem cells send by the foetus affect the mother.??

Asked by Ahijeet | 26th Mar, 2017, 02:38: PM

Expert Answer:

Here you question is about the condition erythroblastosis foetalis.
It will not affect the mother but it will affect the child she is carrying during second pregnancy.
  • An Rh-negative (Rh) woman may become sensitive if she carried an Rh+ child.
  • Rh antigens of the foetus do not get exposed to the Rh blood of the mother in the first pregnancy because the blood of the two is well separated by the placenta.
  • However, during the delivery of the first child, there is a possibility of exposure of maternal blood to the Rh+ blood of the first child. 
  • It sensitises the mother, and the mother’s body starts producing antibodies against the
    Rh+ antigens.
  • During the second pregnancy, if the child is Rh+, then there may be blood trouble.
  • The mother’s Rh antibodies can leak into the blood of the Rh+ foetus which may destroy RBCs in the foetus.
  • This may cause severe anaemia or jaundice in the baby, or it may sometimes even lead to the death of the foetus and abortion.

Answered by Hemangi Binny | 27th Mar, 2017, 10:45: AM