NEET Class neet Answered
What determines, which one of the homologous chromosome's (ie, whether father's or mother's ) will be transcribed for expression of a particular gene?
Asked by sumayiah2000 | 01 Sep, 2019, 03:54: PM
Expert Answer
- In the majority of cases, two copies of each chromosome — and therefore, two copies of each gene — arrive in every fertilized egg.
- However, in some cases, one of the genes within a pair is somehow switched "off"; this occurs because of the process known as imprinting.
- The inactivation of particular genes in this way depends on which parent the genes were inherited from. In such cases, a gene is only expressed when it comes from the designated or "correct" parent.
- Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner.
- In particular, when the gene at a maternally imprinted locus is expressed, the copy of the imprinted gene from the mother is always turned "off," whereas the copy from the father is always turned "on." The opposite is true of a paternally imprinted gene.
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