CBSE Class 12-science Answered
Explain the process of producing genetically engineered insulin.
Asked by JASKAMAL KAUR | 05 Oct, 2015, 06:38: PM
Expert Answer
Hi Jaskamal,
In 1983, Eli Lilly, an American company, first prepared two DNA sequences corresponding to the A and B chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin or humulin.
Answered by | 05 Oct, 2015, 06:46: PM
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