Which sequence of RNA is transcribed from a hypothetical sequence of DNA given below?
Explain in detail.
In a DNA sequence, the strand which reads in the 5’-3’ direction is the coding strand which contains the genetic information to be transcribed. The other strand in the 3’-5’ direction is the template strand which is complementary to the coding strand.
If we take the template strand and build a new DNA strand on it, we would get an exact copy of the original DNA coding strand formed. RNA transcription occurs in a similar fashion. If we build an RNA strand on the template strand, we will get a copy of the information on the DNA coding strand - but with one important difference. In RNA, uracil (U) is used instead of thymine (T).
With reference to our question, the given hypothetical sequence of DNA is as follows:
It is known that the sequence of mRNA is same as the coding strand of DNA. However, in RNA, thymine is replaced by uracil.
Hence, the sequence of mRNA will be 5'-UACGUACGUACGUACG-3'.