Wed January 02, 2013 By: Vaibhav Srivastava

Disease caused by dominant allele located on x chromosome?

Expert Reply
Thu January 03, 2013

X-linked dominant inheritance is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome. This inheritance indicates that a gene responsible for a genetic disorder is located on the X chromosome, and only one copy of the allele is sufficient to cause the disorder when inherited from a parent who has the disorder.

An example is Vitamin D resistant rickets - X-linked hypophosphatemia.

Other examples are:? 

  • Rett syndrome?
  • Fragile X syndr?ome
  • Most cases of ?Alport syndrome
  • Charcot–Marie–Tooth disease
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