What are check points in Cell Cycle?
Asked by harinderamit1234
20th September 2018,
8:22 PM
Answered by Expert
Answer:
A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be halted until conditions are favourable. These checkpoints occur near the end of G1, at the G2/M transition, and during metaphase
1. The G1 phase is the interval phase between mitosis and the initiation of DNA replication
2. The duration of the G1 phase is highly variable. The cells which divide frequently have a shorter G1 phase, while the cells which divide less frequently have a longer G1 phase.
3. The G1 phase can be terminated by various stimuli. However, when a cell has completed the G1 phase and enters the S phase, it cannot be terminated.
3. The G1 phase can be terminated by various stimuli. However, when a cell has completed the G1 phase and enters the S phase, it cannot be terminated.
G2 Phase or Pre-mitotic Gap Phase
1. The G2 phase is a stage of further growth of the cell and preparation for its division2. The G2 phase lasts for 2–5 hours.
3. Some proteins formed in the G2 phase cause condensation of chromosomes to initiate mitosis
M Phase or Mitotic Phase
- The mitotic or M phase follows interphase. It starts with nuclear division, corresponding to the separation of daughter chromosomes (karyokinesis) and usually ends with the division of the cytoplasm (cytokinesis).
- After karyokinesis, mitosis is followed immediately by an equal division of the cytoplasm, dividing the cell organelles and macromolecules approximately equally between the daughter cells.
- Cytokinesis is followed by the separation of two diploid daughter cells.
- The M phase lasts for only about an hour.
- After completion of mitosis, the daughter cells may enter the G1 phase of the next cell cycle or the
G0 phase.
Answered by Expert
21st September 2018,
9:24 AM
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