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ICSE Class 10 Answered

WHy do people living at high altitudes have high no.of RBC's?
Asked by pb_ckt | 15 Feb, 2019, 12:14: PM
answered-by-expert Expert Answer

As we move from low altitude to high altitude, the air starts getting thinner and thinner. The partial pressure of oxygen starts decreasing with increasing altitude. Now, since the partial pressure of oxygen is less in our lungs, the binding of oxygen to haemoglobin in RBCs also decreases. As a result, there is decreased oxygen supply to the tissues thereby starving them of oxygen. This situation leads to the release of the hormone erythropoietin from the kidneys, which stimulates the bone marrow to increase the production of RBCs.

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