CBSE - XII Science - Biology - Molecular Basis of Inheritance
What is RFLP and what is its work?
Restriction Fragment Length Polymorphism (RFLP) is a difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples with specific restriction endonucleases. RFLP, as a molecular marker, is specific to a single clone/restriction enzyme combination.
The RFLP probes are frequently used in genome mapping and also finds use in genotyping, forensics, paternity tests, hereditary disease diagnostics, etc.
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