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CBSE - XII Science - Biology - Molecular Basis of Inheritance

What is RFLP and what is its work?

Asked by Areeba Ahmad 15th March 2015, 11:57 PM
Answered by Expert


Restriction Fragment Length Polymorphism (RFLP) is a difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples with specific restriction endonucleases. RFLP, as a molecular marker, is specific to a single clone/restriction enzyme combination.

The RFLP probes are frequently used in genome mapping and also finds use in genotyping, forensics, paternity tests, hereditary disease diagnostics, etc.

Answered by Expert 16th March 2015, 9:48 AM

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