WHAT IS MEANT BY OSSIFICATION OF BONES ? EXPLAIN.
- The process of formation of bones is called ossification. It is the gradual transition from a fibrous or a cartilaginous template to a bone. The formation of bone is actually the conversion of other types of connective tissues into bone.
- Ossification occurs at certain sites known as centers of ossification.
- The process is initiated by the activity of osteoblasts. Osteoblasts are bone forming cells and secrete collagen and other substances that form the ground substance of bone.
- The centers of ossification may be primary or secondary.
- The primary centers of ossification appear before birth and are the first to start the process of ossification.
- The secondary centers of ossification mostly appear after birth. The secondary centers are sites where process of ossification starts after it has started in primary centers.
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