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Explain the renin-angiotensin mechanism.


Asked by Topperlearning User 15th June 2016, 10:41 AM
Answered by Expert

A fall in glomerular blood pressure activates the juxta glomerular cells to release renin.



Renin converts angiotensin, first to angiotensin I and then to angiotensin II.



Angiotensin II increases the glomerular blood pressure which increases the glomerular filtrate rate (GFR).



At the same time, angiotensin II activates the adrenal cortex to release aldosterone.



Aldosterone stimulates the reabsorption of sodium ions and water from DCT. This also results in an increase in GFR.


Answered by Expert 15th June 2016, 12:41 PM
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