CBSE Class 12-science Answered
Differences between autoimmune and immunodeficiency diseases:
Characteristics |
Autoimmune diseases |
Immunodeficiency diseases |
Cause |
Caused by an overactive immune system in the absence of a pathogen |
Caused by an insufficient immune response in the presence of a pathogen or opportunistic organism |
Age |
Common in middle age people |
Age distribution varies depending on the underlying cause. |
Sex |
Common among females |
No specific sex distribution |
Course |
Has a remitting and relapsing course |
Static and may increase in severity with time |
Etiology |
Multifactorial |
Caused by a specific genetic defect or environmental cause |
Diagnosis |
Diagnosed by immune biomarkers which detect typical associations of symptoms and signs |
Diagnosed by detecting the missing component of the immune system by specific laboratory assays |
Treatment |
Treated with immune suppressants |
Treated by replacing the missing component with transfusions, prevention of infections with immunization and prophylaxis or in selected cases with stem cell transplantation |
Examples |
Graves’ disease |
Severe combined immunodeficiency (SCID) |