Why Doesn't Blood coagulate inside our blood vessels ?

Asked by  | 22nd Jan, 2010, 07:05: PM

Expert Answer:

Due to the following:

i) Endothelial surface factor - Smoothness of the endothelium prevents contact activation of intrinsic clotting system. Also presence of monomolecular layer of protein attached to the inner surface of endothelium repels the platelets and clotting factor, thus preventing clotting.

ii) Speed of blood flow - It prevents the intravascular coagulation

iii) Presence of natural anti-coagulants such as heparin, fibrin and antithrombin and absence of coagulation factor or thromboplastin

Answered by  | 22nd Jan, 2010, 07:32: PM

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