How phenol is used in the manufacture of drugs like aspirin?

Asked by Topperlearning User | 27th Mar, 2014, 03:43: PM

Expert Answer:

  •  Phenol first needs to be treated with NaOH  that will give sodium phenoxide.
  • Sodium phenoxide when treated with CO2 at 400K under 4-7 atm pressure followed by acidification gives 2-hydroxy benzoic acid (salicylic acid as the main product).
  • Salicyclic acid is the starting material for the manufacture of 2-Acetoxybenzoic acid(aspirin) which is used for relieving pain and to bring down the body temperature.

Answered by  | 27th Mar, 2014, 05:43: PM