Difference betwwen
Glycolysis and kerbs cycle

Asked by sree_jhumki | 25th Jul, 2017, 04:47: PM

Expert Answer:

Differences between Glycolysis and Krebs Cycle:

Glycolysis

Krebs cycle

  • It takes place in the cytoplasm.
  • It takes place in the mitochondria.
  • It is a linear pathway.
  • It is a cyclic pathway.
  • Oxygen is not required for glycolysis.
  • It takes place only in the presence of oxygen, used as terminal oxidant.
  • It is a pathway for both aerobic and anaerobic respiration.
  • It occurs in aerobic respiration only.
  • Carbon dioxide is not evolved.
  • Carbon dioxide is evolved during the cycle.
  • Glycolysis is the first step in the respiration.
  • Krebs cycle is the second stage in the respiration.
  • Glucose is the substrate used in glycolysis.
  • Acetyl coenzyme A is the substrate in Krebs cycle.
  • 2 ATP molecules are used up in this process.
  • No ATP molecules are consumed.
  • Produces 4 ATP molecules, so net gain is 2 ATP.
  • Produces 2 GTP molecules from 2 pyruvate molecules.
  • Pyruvic acid is the end product of glycolysis which undergoes oxidative decarboxylation and enters the Krebs cycle.
  • Oxalo acetic acid is the end product of Krebs cycle which again gets cycled by combing with acetyl CoA in the next cycle.
  • 1 molecule glucose yields 2NADH + H+.
  • 2 pyruvate molecules yield 6 NADH + H+ and FADH2 molecules.

Answered by Sheetal Kolte | 25th Jul, 2017, 05:27: PM