Conversion of amines
Asked by Sudamkalgunde624
| 31st Dec, 2019,
11:38: AM
Expert Answer:
Conversion of Amines:
1. Acylation reaction
- Aliphatic and aromatic primary and secondary amines (which contain replaceable hydrogen atoms) react with acid chlorides, anhydrides and esters to form substituted amide.
- The process of introducing an acyl group (R–CO–) into the molecule is called acylation.
- The reaction is carried out in the presence of a stronger base than the amine, such as pyridine, which removes HCl formed and shifts the equilibrium to the product side.
2. Carbylamine reaction
- On heating aliphatic and aromatic primary amines with chloroform and ethanolic KOH they form isocyanides or carbylamines which have foul odour.
- Secondary and tertiary amines do not show this reaction.
- This reaction is used as a test for primary amines.
Answered by Varsha
| 31st Dec, 2019,
03:30: PM
Concept Videos
- sir/madam, this doubt will be lenghty. request peace reading. the doubt is w.r.t chapter Amines; to be specific it is w.r.t basicity of amines. in the topic of the comparision of the basic character of alkylamines with ammonia, the order of basicity of amines is tertiary> secondary> primary in gaseous phase, only due to the +I effect. in gasous phase only +I effect is shown? also in the aqueous phase, the disturbancy in the order of basicity is due to the sum of effects of +I effect, solvation effect and steric hindrance? the order of the stability of the following in aqueous phase: +I effect: tertiary> secondary> primary solvation: primary > secondary > tertiary steric hindrance: primary > secondary > tertiary so does it means that +I is effected in both gaseous and aqueous phase but solvation and steric hindrance are effected only in aqueous phase? also sir there is an order of basicity when R= CH3 group and when R= C2H5 group: R= CH3: secondary> primary> tertiary R= C2H5: secondary> tertiary> primary so sir can we generalise the order that: when R=CH3 group, the order of basicity: secondary> primary> tertiary and when R> CH3 group, the order of basicity: secondary> tertiary> primary
- sir/ madam, is it true that if no of bonds in an atom increases then the atom acquires a positive charge on it and when it loses one bond it acquires a negative charge on it ? why does it happen so?
- pls explain
- What is the product of this amide acylation?
- Please answer this question.
- Why toluene is more reactive than nitro benzene?
- Question 6. Option 2nd and 3rd
-
Z is :-
(1)
CH3—CH2—OH
(2)
CH3—NH2
(3)
CH3—OH
(4)
CH3—CH2—NH2
- Which amine salts are used for determining molecular masses of amines?
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