Conversion of amines 

 

Asked by Sudamkalgunde624 | 31st Dec, 2019, 11:38: AM

Expert Answer:

Conversion of Amines:   

1. Acylation reaction

  • Aliphatic and aromatic primary and secondary amines (which contain replaceable hydrogen atoms) react with acid chlorides, anhydrides and esters to form substituted amide.
  • The process of introducing an acyl group (R–CO–) into the molecule is called acylation.
  • The reaction is carried out in the presence of a stronger base than the amine, such as pyridine, which removes HCl formed and shifts the equilibrium to the product side.
 
2. Carbylamine reaction
  • On heating aliphatic and aromatic primary amines with chloroform and ethanolic KOH they form isocyanides or carbylamines which have foul odour.
  • Secondary and tertiary amines do not show this reaction.
  • This reaction is used as a test for primary amines.

       

Answered by Varsha | 31st Dec, 2019, 03:30: PM