Question
Mon December 24, 2012 By: Shrijeet

hoffman bromide degradation reaction....

Expert Reply
Mon December 24, 2012
By this method the amide (–CONH2) group is converted into primary amino (– NH2) group.
 
R - CO - NH2 + Br2 + 4KOH ? R - NH2 + 2KBR + K2CO3 + 2H2

 

 

               Amide                             Pri-amine     
This is the most convenient method for preparing primary amines.
 
This method gives an amine containing one carbon atom less than amide.
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