Question
Sat August 06, 2011 By: Shubham Kaushik

what is unimolecular elimination reaction through conjugate base?

Expert Reply
Mon August 08, 2011
The E1cB elimination reaction is a special type of elimination reaction in organic chemistry.The abbreviation stands for Elimination Unimolecular conjugate Base. This reaction mechanism explains the formation of alkenes from (mostly) alkyl halides through a carbanion intermediate given specified reaction conditions and specified substrates.The reaction takes place around a sp3 - sp3 carbon to carbon covalent bond with an ?-acidic hydrogen atom substituent and a ?-leaving group
A strong base abstracts the ? proton generating a carbanion. The electron pair then expels the leaving group and the double bond is formed.
 
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